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Relevance: DAMGO is utilized for the reference whole agonist in scientific research investigating the phosphorylation profiles of MOR. Although both equally of People DAMGO and SR-17018 induce MOR phosphorylation, they show unique temporal dynamics, with SR-17018 inducing extended phosphorylation. [
The synthesis of SR17018 entails quite a few intricate steps that use many chemical reactions. An in depth Evaluation reveals the compound's synthesis begins from distinct precursor molecules, which undergo transformations which includes esterification, reduction, and coupling reactions.
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Esterification: The process begins with the esterification of the unnatural amino acid to type an intermediate.
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